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A fresh look at the validity of the diffusion approximation for modeling fluorescence spectroscopy in biological tissue
conference contribution
posted on 2012-01-01, 00:00 authored by Chintha Handapangoda, M Premaratne, Saeid NahavandiFluorescence has become a widely used technique for applications in noninvasive diagnostic tissue spectroscopy. The standard model used for characterizing fluorescence photon transport in biological tissue is based on the diffusion approximation. On the premise that the total energy of excitation and fluorescent photon flows must be conserved, we derive the widely used diffusion equations in fluorescence spectroscopy and show that there must be an additional term to account for the transport of fluorescent photons. The significance of this additional term in modeling fluorescence spectroscopy in biological tissue is assessed.
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Event
IEEE Engineering in Medicine and Biology Society. Conference (34th : 2012 : San Diego, California)Pagination
1494 - 1497Publisher
IEEELocation
San Diego, CaliforniaPlace of publication
Piscataway, N.J.Publisher DOI
Start date
2012-08-28End date
2012-09-01ISBN-13
9781424441198ISBN-10
1424441196Language
engPublication classification
E1 Full written paper - refereedTitle of proceedings
EMBC 2012 : Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology SocietyUsage metrics
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