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Design and evaluation of a microcantilever aptasensor

conference contribution
posted on 2014-01-01, 00:00 authored by Yang Lim, Abbas KouzaniAbbas Kouzani, Wei DuanWei Duan, Xiujuan Dai, Akif KaynakAkif Kaynak, D Mair
Aptamers enhance flexibility in biosensor design. An aptasensor employs aptamers as a biological recognition element for biosensing. This paper presents design, fabrication, and evaluation of a microcantilever aptasensor. To identify and avoid potential bottlenecks in the aptasensor design, the parameters of the aptasensor are investigated through modelling and simulation. Next, thin SU-8 microcantilevers are fabricated to form the aptasensor. Characterization of the fabricated aptasensor is presented. Next, a plasma-based surface funtionalisation method is used to immobilize aptamers on the atasensor. Finally, an evaluation of the performance of the aptasensor is performed through detection of thrombin molecules. The evaluation results are presented and discussed. © 2014 IEEE.

History

Event

IEEE International Symposium on Circuits and Systems (2014 : Melbourne, Victoria)

Pagination

221 - 224

Publisher

IEEE

Location

Melbourne, Victoria

Place of publication

Piscataway, N.J.

Start date

2014-06-01

End date

2014-06-05

ISSN

0271-4310

ISBN-13

9781479934324

Language

eng

Publication classification

E Conference publication; E1 Full written paper - refereed

Copyright notice

2014, Institute of Electrical and Electronics Engineers Inc.

Editor/Contributor(s)

[Unknown]

Title of proceedings

ISCAS 2014 : Proceedings of the 2014 IEEE International Symposium on Circuits and Systems

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