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Dielectrophoresis of micro/nano particles using curved microelectrodes

conference contribution
posted on 2011-01-01, 00:00 authored by Khashayar Khoshmanesh, F Tovar-Lopez, Sara Baratchi, C Zhang, A Kayani, A Chrimes, Saeid Nahavandi, D Wlodkowic, A Mitchell, K Kalantar-zadeh
Dielectrophoresis, the induced motion of polarisable particles in non-homogenous electric field, has been proven as a versatile mechanism to transport, immobilise, sort and characterise micro/nano scale particle in microfluidic platforms. The performance of dielectrophoretic (DEP) systems depend on two parameters: the configuration of microelectrodes designed to produce the DEP force and the operating strategies devised to employ this force in such processes. This work summarises the unique features of curved microelectrodes for the DEP manipulation of target particles in microfluidic systems. The curved microelectrodes demonstrate exceptional capabilities including (i) creating strong electric fields over a large portion of their structure, (ii) minimising electro-thermal vortices and undesired disturbances at their tips, (iii) covering the entire width of the microchannel influencing all passing particles, and (iv) providing a large trapping area at their entrance region, as evidenced by extensive numerical and experimental analyses. These microelectrodes have been successfully applied for a variety of engineering and biomedical applications including (i) sorting and trapping model polystyrene particles based on their dimensions, (ii) patterning carbon nanotubes to trap low-conductive particles, (iii) sorting live and dead cells based on their dielectric properties, (iv) real-time analysis of drug-induced cell death, and (v) interfacing tumour cells with environmental scanning electron microscopy to study their morphological properties. The DEP systems based on curved microelectrodes have a great potential to be integrated with the future lab-on-a-chip systems.

History

Event

Smart Nano-Micro Materials and Devices. Conference (2011 : Hawthorn, Vic.)

Pagination

1 - 9

Publisher

SPIE

Location

Hawthorn, Vic.

Place of publication

Bellingham, Wash.

Start date

2011-12-05

End date

2011-12-07

ISSN

0277-786X

ISBN-13

9780819488459

Language

eng

Notes

Reproduced with the kind permission of the copyright owner.

Publication classification

E1 Full written paper - refereed

Copyright notice

2011, SPIE

Editor/Contributor(s)

S Juodkazis, M Gu

Title of proceedings

SPIE 2011 : Proceedings of SPIE - The International Society for Optical Engineering