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A potential application of a piezoelectric atomiser for ophthalmic drug delivery

journal contribution
posted on 2007-03-01, 00:00 authored by W Xia, H Y Hsu, Lingxue KongLingxue Kong, A Evans, R Lee
A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the atomising process. An optimal condition is determined for producing a stream of droplets. The study shows that the droplet size and the spraying velocity are suitable for ophthalmic drug delivery application, with an even distribution of the drug over most of the eyeball surface area due to the controllable cross-sectional area of the droplet stream. This greatly improves the treatment effectiveness and efficiency of eye therapy. Finally, a structure of the ophthalmic drug delivery system is proposed.

History

Journal

Applied bionics and biomechanics

Volume

4

Issue

1

Pagination

9 - 17

Publisher

Taylor & Francis

Location

Abingdon, England

ISSN

1176-2322

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2007, Taylor & Francis

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