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A randomized controlled single blind study of the efficacy of clonazepam and lithium in the treatment of acute mania
journal contribution
posted on 1997-07-01, 00:00 authored by H M Clark, Michael BerkMichael Berk, S BrookThis study is a randomized controlled trial of 40 patients suffering from bipolar affective disorder, manic phase (DSM IV). The patients were treated with either clonazepam or lithium. There were no differences between the two groups at 4 weeks on any of the efficacy measures, which included the BPRS, MAS, CGI and GAF scales. Side-effects were comparably mild in both groups. Clonazepam may be an effective treatment for acute mania.
History
Journal
Human psychopharmacologyVolume
12Issue
4Season
July / AugustPagination
325 - 328Publisher
WileyLocation
Chichester, Eng.ISSN
0885-6222Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
1997, John Wiley & Sons, Ltd.Usage metrics
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