stambas-cladecountry-2005.pdf (317.57 kB)
Clade, country and region-specific HIV-1 vaccines : are they necessary?
journal contribution
posted on 2005-01-01, 00:00 authored by K Slobod, C Coleclough, S Brown, John StambasJohn Stambas, X Zhan, S Surman, B Jones, A Zirkel, P Freiden, B Brown, R Sealy, M Bonsignori, J HurwitzToday, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.