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Consensus recommendations for the diagnosis, treatment and control of Mycobacterium ulcerans infection (Bairnsdale or Buruli ulcer) in Victoria, Australia
journal contribution
posted on 2007-01-15, 00:00 authored by P D R Johnson, J A Hayman, T Y Quek, J A M Fyfe, G A Jenkin, J A Buntine, Eugene AthanEugene Athan, M Birrell, J Graham, C J Lavender, Mycobacterium ulcerans Study TeamMycobacterium ulcerans causes slowly progressive, destructive skin and soft tissue infections, known as Bairnsdale or Buruli ulcer (BU). Forty-six delegates with experience in the management of BU attended a 1-day conference in Melbourne on 10 February 2006, with the aim of developing a consensus approach to the diagnosis, treatment and control of BU. An initial draft document was extended and improved during a facilitated round table discussion. BU is an environmental infection that occurs in specific locations. The main risk factor for infection is contact with an endemic area. Prompt cleaning of abrasions sustained outdoors, wearing protective clothing, and avoiding mosquito bites may reduce an individual's risk of infection. BU can be rapidly and accurately diagnosed by polymerase chain reaction testing of ulcer swabs or biopsies. Best outcomes are obtained when the diagnosis is made early. To aid early diagnosis, health authorities should keep local populations informed of new outbreaks. BU is best treated with surgical excision, which, if possible, should include a small rim of healthy tissue. For small lesions this may be all that is required. However, there is a role for antibiotics for more extensive disease, and their use may allow more conservative surgery.
History
Journal
The Medical journal of AustraliaVolume
186Issue
2Pagination
64 - 68Publisher
Australasian Medical Publishing Company LtdLocation
Strawberry Hills, N.S.W.ISSN
0025-729XLanguage
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2007, Medical Journal of AustraliaUsage metrics
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No categories selectedKeywords
HumansMycobacterium Infections, NontuberculousMycobacterium ulceransSkin Diseases, BacterialSkin UlcerVictoriaScience & TechnologyLife Sciences & BiomedicineMedicine, General & InternalGeneral & Internal MedicinePHILLIP-ISLANDRISK-FACTORSRIFAMPINDISEASESTREPTOMYCINEMERGENCEAMIKACINOUTBREAKREGIONMycobacterium ulcerans Study Team
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