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Electrophoretic separations on paper: past, present, and future-a review

journal contribution
posted on 2017-09-08, 00:00 authored by Pavisara Nanthasurasak, Joan Marc Cabot, Hong Heng See, Rosanne GuijtRosanne Guijt, Michael C Breadmore
Point-of-collection (POC) devices aim for a fast, on-site detection for medical and environmental purposes. In this area, microfluidic Paper-based Analytical Devices (μPADs) have recently gained popularity because these are potentially cheap and environmentally friendly to produce, and easy to use. From an analytical perspective, paper is well known for its use as a substrate for chromatography, but less known for its use in electrophoretic separations. With the recent interest in μPADs, most applications are based on rather simple assays with relatively few applications incorporating an analytical separation. The focus of this review is on paper-based electrophoresis, originating with the key developments in the 1940s and 1950s as well as the recent developments of electrophoretic μPADs, and concluding with a critical discussion of the opportunities and challenges for electrophoretic μPADS in the future.

History

Journal

Analytica chimica acta

Volume

985

Pagination

7 - 23

Publisher

Elsevier

Location

Amsterdam, The Netherlands

ISSN

0003-2670

eISSN

0003-2670

Language

eng

Publication classification

C Journal article; C1.1 Refereed article in a scholarly journal

Copyright notice

2017, Elsevier B.V.