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Evidence accumulation during perceptual decisions in humans varies as a function of dorsal frontoparietal organization
journal contribution
posted on 2020-08-01, 00:00 authored by M B Brosnan, K Sabaroedin, Tim SilkTim Silk, S Genc, D P Newman, G M Loughnane, A Fornito, R G O’Connell, M A BellgroveAnimal neurophysiological studies have identified neural signals within dorsal frontoparietal areas that trace a perceptual decision by accumulating sensory evidence over time and trigger action upon reaching a threshold. Although analogous accumulation-to-bound signals are identifiable on extracranial human electroencephalography, their cortical origins remain unknown. Here neural metrics of human evidence accumulation, predictive of the speed of perceptual reports, were isolated using electroencephalography and related to dorsal frontoparietal network (dFPN) connectivity using diffusion and resting-state functional magnetic resonance imaging. The build-up rate of evidence accumulation mediated the relationship between the white matter macrostructure of dFPN pathways and the efficiency of perceptual reports. This association between steeper build-up rates of evidence accumulation and the dFPN was recapitulated in the resting-state networks. Stronger connectivity between dFPN regions is thus associated with faster evidence accumulation and speeded perceptual decisions. Our findings identify an integrated network for perceptual decisions that may be targeted for neurorehabilitation in cognitive disorders.
History
Journal
Nature Human BehaviourVolume
4Issue
8Pagination
844 - 855Publisher DOI
eISSN
2397-3374Publication classification
C1 Refereed article in a scholarly journalUsage metrics
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Social SciencesScience & TechnologyLife Sciences & BiomedicinePsychology, BiologicalMultidisciplinary SciencesNeurosciencesPsychology, ExperimentalPsychologyScience & Technology - Other TopicsNeurosciences & NeurologyWHITE-MATTER CHANGESRESTING-STATEMOTOR CORTEXCONFOUND REGRESSIONNEURAL MECHANISMSNEURONAL-ACTIVITYPREMOTOR CORTEXMOTION ARTIFACTGLOBAL SIGNALHUMAN BRAIN
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