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Ewing's sarcoma t(11;22) in a case of acute nonlymphocytic leukemia

journal contribution
posted on 1991-09-01, 00:00 authored by J M Hawkins, Jeffrey CraigJeffrey Craig, L M Secker-Walker, H G Prentice, A B Mehta
Chromosome analysis of bone marrow cells from a patient with acute nonlymphocytic leukemia M2 revealed the translocation t(11;22)(q24;q12) usually associated with Ewing's sarcoma. Molecular investigations ruled out the possibility that this was a variant Philadelphia translocation with breakpoints in the major breakpoint cluster region. Although cytogenetic analysis was not available at diagnosis, this abnormality was found both pre- and postallogeneic bone marrow transplant.

History

Journal

Cancer genetics and cytogenetics

Volume

55

Issue

2

Pagination

157 - 162

Publisher

Elsevier

Location

Amsterdam, The Netherlands

ISSN

0165-4608

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

1991, Elsevier Science Publishing Co., Inc.