Deakin University
Browse

File(s) under permanent embargo

Hemolytic-uremic syndrome following urinary tract infection with enterohemorrhagic Escherichia coli: case report and review

journal contribution
posted on 1998-08-01, 00:00 authored by M Starr, V Bennett-Wood, A K Bigham, Tania De Koning-WardTania De Koning-Ward, A M Bordun, D Lightfoot, K A Bettelheim, C L Jones, R M Robins-Browne
A 6-week-old child with acute urinary tract infection caused by Shiga toxin-producing Escherichia coli (STEC) O5:H-developed hemolytic-uremic syndrome (HUS). Molecular and phenotypic analysis of the urinary isolate indicated that it lacked uropathic properties and that it was probably of intestinal origin. Nevertheless, the patient did not experience a diarrheal prodrome, nor was STEC or Shiga toxin detected in his feces at any time. Examination of the patient's serum pointed to recent infection with E. coli O5, with no evidence of exposure to E. coli O157, O111, or O26. A review of 13 previously reported cases of HUS associated with acute urinary tract infection indicated that this was the first case of nondiarrheal HUS in which infection with the most common STEC serogroups was specifically excluded. This case illustrates the need to investigate patients with nondiarrheal HUS for infection with STEC.

History

Journal

Clinical infectious diseases

Volume

27

Issue

2

Pagination

310 - 315

Publisher

Oxford University Press

Location

Oxford, Eng.

ISSN

1058-4838

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

1998, Infectious Diseases Society of America