alexandersen-middleeastrespiratory-2014.pdf (207.85 kB)
Middle East respiratory syndrome coronavirus antibody reactors among camels in Dubai, United Arab Emirates, in 2005
journal contribution
posted on 2014-04-01, 00:00 authored by Soren AlexandersenSoren Alexandersen, G P Kobinger, G Soule, U WerneryWe tested, using a low starting dilution, sequential serum samples from dromedary camels, sheep and horses collected in Dubai from February/April to October of 2005 and from dromedary camels for export/import testing between Canada and USA in 2000-2001. Using a standard Middle East respiratory syndrome coronavirus (MERS-CoV) neutralization test, serial sera from three sheep and three horses were all negative while sera from 9 of 11 dromedary camels from Dubai were positive for antibodies supported by similar results in a MERS-CoV recombinant partial spike protein antibody ELISA. The two negative Dubai camels were both dromedary calves and remained negative over the 5 months studied. The six dromedary samples from USA and Canada were negative in both tests. These results support the recent findings that infection with MERS-CoV or a closely related virus is not a new occurrence in camels in the Middle East. Therefore, interactions of MERS-CoV at the human-animal interface may have been ongoing for several, perhaps many, years and by inference, a widespread pandemic may be less likely unless significant evolution of the virus allow accelerated infection and spread potential in the human population.
History
Journal
Transboundary and emerging diseasesVolume
61Issue
2Pagination
105 - 108Publisher
WileyLocation
London, Eng.Publisher DOI
Link to full text
ISSN
1865-1682eISSN
1865-1682Language
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2014, WileyUsage metrics
Categories
No categories selectedKeywords
Middle EastMiddle East respiratory syndrome coronavirusantibodiescamelscoronavirusdromedariesAnimalsAntibodies, ViralCoronavirus InfectionsHorsesIncidenceNeutralization TestsSheepSyndromeUnited Arab EmiratesScience & TechnologyLife Sciences & BiomedicineInfectious DiseasesVeterinary SciencesSUSCEPTIBILITYDROMEDARIUSPNEUMONIA
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC