File(s) under permanent embargo
Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms
journal contribution
posted on 2017-01-01, 00:00 authored by Jagat Kanwar, Rasika Samarasinghe, S K Kamalapuram, Rupinder KanwarIncreasing evidence suggests that stem cells, a small population of cells with unique self-renewable and tumour regenerative capacity, are aiding tumour re-growth and multidrug resistance. Conventional therapies are highly ineffective at eliminating these cells leading to relapse of disease and formation of chemoresistance tumours. Cancer and stem cells targeted therapies that utilizes nanotherapeutics to delivery anti-cancer drugs to specific sites are continuously investigated. This review focuses on recent research using nanomedicine and targeting entities to eliminate cancer cells and cancer stem cells. Current nanotherapeutics in clinical trials along with more recent publications on targeted therapies are addressed.
History
Journal
Mini reviews in medicinal chemistryVolume
17Issue
18Pagination
1 - 8Publisher
Bentham Science PublishersLocation
Beijing, ChinaPublisher DOI
ISSN
1389-5575eISSN
1875-5607Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2017, Bentham Science PublishersUsage metrics
Categories
No categories selectedKeywords
Science & TechnologyLife Sciences & BiomedicineChemistry, MedicinalPharmacology & PharmacyAptamerscancerchemotherapeuticsstem cellsnanotherapeuticsnanomedicineMAGNETIC NANOPARTICULATE PROBESPOLYMERIC MICELLE FORMULATIONIRON-OXIDE NANOPARTICLESPHASE-II TRIALDRUG-DELIVERYIN-VIVOPEG NANOPARTICLESCONTRAST AGENTSCREMOPHOR-FREEBREAST-CANCER
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC