ackland-peanutallergens-2014.pdf (1.58 MB)
Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures
journal contribution
posted on 2014-01-01, 00:00 authored by Dwan Price, Leigh AcklandLeigh Ackland, W Burks, M I Knight, Cenk SuphiogluCenk SuphiogluAllergen absorption by epithelia may play an important role in downstream immune responses. Transport mechanisms that can bypass Peyer's patches include transcellular and paracellular transport. The capacity of an allergen to cross via these means can modulate downstream processing of the allergen by the immune system. The aim of this study was to investigate allergen-epithelial interactions of peanut allergens with the human intestinal epithelium.
History
Journal
Cellular Physiology and BiochemistryVolume
33Issue
6Pagination
1758 - 1777Publisher
S. Karger AGLocation
Basel, SwitzerlandPublisher DOI
ISSN
1421-9778eISSN
1421-9778Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2014, S. Karger AGUsage metrics
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No categories selectedKeywords
AllergenCaco-2EpitheliaPeanutPermeabilityTight junctionTransportScience & TechnologyLife Sciences & BiomedicineCell BiologyPhysiologyARA H 1IGE-BINDING EPITOPESCOLORECTAL-CANCER CELLSMAJOR SOYBEAN ALLERGENADHESION MOLECULEEPITHELIAL-CELLSIN-VITROMUTATIONAL ANALYSISENDOTHELIAL-CELLSCHOLERA-TOXINPROTEINZO-1
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