Prevention of recurrent fetal death in utero due to group B streptococcal chorioamnionitis

Maternal colonisation with group B Streptococcus (GBS) is
a well recognised cause of neonatal sepsis.1 Colonisation of
the infant at delivery results in invasive disease in 1–2% of
neonates with a 5% mortality.2 Routine antenatal screening is
recommended and prophylaxis offered to colonised women.
We report a case of recurrent mid-trimester fetal death in
utero, caused by GBS chorioamnionitis, and a subsequent
successful pregnancy achieved with intermittent amoxicillin
therapy from 12 weeks’ gestation.