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Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence
journal contribution
posted on 2018-03-01, 00:00 authored by Miaobing ZhengMiaobing Zheng, Karen Lamb, Carley GrimesCarley Grimes, Rachel LawsRachel Laws, Kristy BoltonKristy Bolton, K K Ong, Karen CampbellKaren CampbellThe contribution of rapid weight gain (RWG) during infancy to later adiposity has received considerable investigation. The present systematic review and meta-analysis aimed to update the literature on association between RWG and subsequent adiposity outcomes. Electronic searches were undertaken in EMBASE, MEDLINE, psycINFO, PubMed and ScienceDirect. Studies that examined the associations between RWG (a change in weight z-scores > 0.67) during infancy (from birth to age 2 years) and subsequent adiposity outcomes were included. Random effects meta-analysis was conducted to obtain the weighted-pooled estimates of the odds of overweight/obesity for those with RWG. Seventeen studies were eligible for inclusion with the majority of studies (15/17) being of high/acceptable quality and reporting positive associations between RWG during infancy and later adiposity outcomes. RWG in infancy was associated with overweight/obesity from childhood to adulthood (pooled odds ratio = 3.66, 95% confidence interval: 2.59-5.17, I2 > 75%). Subgroup analyses revealed that RWG during infancy was associated with higher odds of overweight/obesity in childhood than in adulthood, and RWG from birth to 1 year was associated with higher odds of overweight/obesity than RWG from birth to 2 years. The present study supports that RWG during infancy is a significant predictor of adiposity in later life.
History
Journal
Obesity reviewsVolume
19Issue
3Pagination
321 - 332Publisher
John Wiley & SonsLocation
Chichester, Eng.Publisher DOI
ISSN
1467-7881eISSN
1467-789XLanguage
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2017, World Obesity FederationUsage metrics
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