hyde-referencerangesfor-2019.pdf (205.13 kB)
Reference ranges for trabecular bone score in Australian men and women: a cross-sectional study
journal contribution
posted on 2019-06-01, 00:00 authored by Kara Anderson, Kara KewKara Kew, Didier Hans, Mark KotowiczMark Kotowicz, Natalie HydeNatalie Hyde, Julie PascoJulie PascoTrabecular bone score (TBS) is a novel method for indirectly assessing trabecular microarchitecture at the lumbar spine, providing information complementary to areal BMD. However, limited reference ranges exist for the normative distribution of TBS, particularly in men. The aim of this study was to develop such a reference range in Australian men and women. This study included 894 men and 682 women (aged 24 to 98 years) enrolled in the Geelong Osteoporosis Study. TBS was determined retrospectively by analysis of lumbar spine DXA scans (Lunar Prodigy) using TBS iNsight software (version 2.2). Multivariable regression techniques were used to determine best‐fit models for TBS incorporating age, height, and weight. Age‐related differences in TBS were best modelled with a linear relationship in men and a cubic relationship in women. Combined best‐fit models for TBS included age and weight in men, and age and height in women. This study provides normative reference ranges for TBS in Australian men and women, and further indicates that TBS may identify individuals at risk for fracture despite normal BMD.
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Journal
JBMR plusVolume
3Issue
6Article number
e10133Pagination
1 - 6Publisher
WileyLocation
Chichester, Eng.Publisher DOI
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ISSN
2473-4039Language
engPublication classification
C1 Refereed article in a scholarly journalUsage metrics
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