martin-symptomaticmanagement-2006.pdf (69.06 kB)
Symptomatic management of calciphylaxis: a case series and review of the literature
journal contribution
posted on 2006-08-01, 00:00 authored by Mark N Polizzotto, Tamsin Bryan, Michael A Ashby, Peter MartinPeter MartinCalciphylaxis, or calcific uremic arteriopathy, is a rare complication of end-stage renal impairment. It is characterized by the development of small vessel vasculopathy with subcutaneous necrosis and ulceration. Intense pain and cutaneous hyperesthesia are prominent features. Mortality rates are high, and the resulting morbidity is significant. While symptomatic management is the mainstay of treatment, it can be challenging. We describe the symptomatic management of a series of three patients with calciphylaxis. Particular emphasis is placed on the use of multimodal analgesia with high-dose opioids, ketamine, and benzodiazepines and on the use of preemptive analgesia.
History
Journal
Journal of pain and symptom managementVolume
32Issue
2Pagination
186 - 190Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
Link to full text
ISSN
0885-3924Language
engPublication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2006, U.S. Cancer Pain Relief CommitteeUsage metrics
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No categories selectedKeywords
Calciphylaxiscalcific uremic arteriopathyvasculopathydialysisischemiacutaneous ulcerationpain controlsymptom managementScience & TechnologyLife Sciences & BiomedicineHealth Care Sciences & ServicesMedicine, General & InternalClinical NeurologyGeneral & Internal MedicineNeurosciences & NeurologyCHRONIC-RENAL-FAILUREVASCULAR CALCIFICATIONHYPERBARIC-OXYGENDIALYSIS PATIENTSINCIDENT PAINTHERAPYPATIENTNECROSISKETAMINE
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