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The characteristics and outcome of infective endocarditis involving implantable cardiac devices

journal contribution
posted on 2014-10-01, 00:00 authored by Eugene AthanEugene Athan
Infection of implantable cardiac electronic devices in particular lead endocarditis (cardiac device infective endocarditis (CDIE)) is an emerging problem with significant morbidity, mortality and health care costs. The epidemiology is characterised with advanced age and health care association in cases presenting within 6 months of implantation. Risk factors include those of the patient, the procedure and the device. Staphylococcal species predominate as the causative organisms. Diagnosis is reliably made by blood cultures and transesophageal echocardiography. Complications include pulmonary and systemic emboli, persistent bacteremia and concomitant valvular involvement. Management includes complete device removal and prolonged antimicrobial therapy. With long-term follow-up to 1 year, the mortality of CDIE is as high as 23 %. It is associated with patient co-morbidities and concomitant valvular involvement and may be prevented by device removal during index admission.

History

Journal

Current infectious disease reports

Volume

16

Issue

12

Article number

446

Pagination

1 - 5

Publisher

Springer

Location

Berlin, Germany

ISSN

1523-3847

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2014, Springer Verlag