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The effect of multiple pulses of light on the circadian phase response of the rat

journal contribution
posted on 1999-06-01, 00:00 authored by Mark StokesMark Stokes, S Kent, S M Armstrong
Multiple pulses of light administered to humans have been reported to result in type 0 phase responses. These results suggest the underlying pacemaker to be nonsimple. At present, results with this type of protocol have only been reported for humans. Therefore, multiple pulses of light were administered to rats. Rats were exposed to one, two, three, or four pulses of light for 5 h (1000 lux) at successive 24-h intervals. Results did not suggest a type 0 phase response. Nonetheless, results with a second, third, or fourth light exposure were not fully predictable from a phase response curve derived from a single light pulse.

History

Journal

Journal of biological rhythms

Volume

14

Issue

3

Pagination

172 - 184

Publisher

Sage

Location

London, Eng.

ISSN

0748-7304

Language

eng

Publication classification

C Journal article; C1.1 Refereed article in a scholarly journal

Copyright notice

1999, Sage