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The influence of sodium salts on binary mixtures of bitter-tasting compounds
journal contribution
posted on 2004-01-01, 00:00 authored by Russell KeastRussell Keast, T Canty, P BreslinIn order to study potential mixture interactions among bitter compounds, selected sodium salts were added to five compounds presented either alone or as binary bitter- ompound mixtures. Each compound was tested at a concentration that elicited ‘weak’ perceived bitterness. The bitter compounds were mixed at these concentrations to form a subset of possible binary mixtures. For comparison, the concentration of each solitary compound was doubled to measure bitterness inhibition at the higher intensity level elicited by the mixtures. The following sodium salts were tested for bitterness inhibition: 100 mM sodium chloride (salty), 100 mM sodium gluconate (salty), 100 and 20 mM monosodium glutamate (umami), and 50 mM adenosine monophosphate disodium salt (umami). Sucrose (sweet) was also employed as a bitterness suppressor. The sodium salts differentially suppressed the bitterness of compounds and their binary combinations. Although most bitter compounds were suppressed, the bitterness of tetralone was not suppressed, nor was the bitterness of the binary mixtures that contained it. In general, the percent suppression of binary mixtures of compounds was predicted by the average percent suppression of its two components. Within the constraints of the present study, the bitterness of mixtures was suppressed by sodium salts and sucrose independently, with few bitter interactions. This is consistent with observations that the bitter taste system integrates the bitterness of multi-compound solutions linearly.
History
Journal
Chemical sensesVolume
29Issue
5Pagination
431 - 439Publisher
Oxford University PressLocation
Oxford, EnglandPublisher DOI
ISSN
0379-864XeISSN
1464-3553Language
engNotes
This is a pre-copy-editing, author-produced PDF of an article accepted for publication by Chemical senses following peer review. The definitive publisher-authenticated version Keast, Russell, Canty, Thomas M. and Breslin, Paul A. S. 2004, The influence of sodium salts on binary mixtures of bitter-tasting compounds, Chemical senses, vol. 29, no. 5, pp. 431-439. is available online at http://dx.doi.org/10.1093/chemse/bjh045Publication classification
C1.1 Refereed article in a scholarly journalCopyright notice
2004, Oxford University PressUsage metrics
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No categories selectedKeywords
binary mixturesbitterness inhibition\/supressionbitter tastesodium saltstaste psychophysicsScience & TechnologyLife Sciences & BiomedicineBehavioral SciencesFood Science & TechnologyNeurosciencesPhysiologyNeurosciences & Neurologybitterness inhibitionsupressionMONOSODIUM GLUTAMATESUPPRESSIONMAGNITUDERESPONSESGUSTDUCINSCALE
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