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Transcriptomic, lipid, and histological profiles suggest changes in health in fish from a pesticide hot spot
journal contribution
posted on 2018-09-01, 00:00 authored by Sharon E Hook, Julie MondonJulie Mondon, Andrew T Revill, Paul A Greenfield, Rachael A Smith, Ryan D R Turner, Patricia CorbettPatricia Corbett, Michael St J WarneBarramundi (Lates calcarifer) were collected at the beginning (1st sampling) and end (2nd sampling) of the wet season from Sandy Creek, an agriculturally impacted catchment in the Mackay Whitsundays region of the Great Barrier Reef catchment area, and from Repulse Creek, located approximately 100 km north in Conway National Park, to assess the impacts of pesticide exposure. Gill and liver histology, lipid class composition in muscle, and the hepatic transcriptome were examined. The first sample of Repulse Creek fish showed little tissue damage and low transcript levels of xenobiotic metabolism enzymes. Sandy Creek fish showed altered transcriptomic patterns, including those that regulate lipid metabolism, xenobiotic metabolism, and immune response; gross histological alterations including lipidosis; and differences in some lipid classes. The second sampling of Repulse Creek fish showed similar alterations in hepatic transcriptome and tissue structure as fish from Sandy Creek. These changes may indicate a decrease in health of pesticide exposed fish.
History
Journal
Marine environmental researchVolume
140Pagination
299 - 321Publisher
ElsevierLocation
Amsterdam, The NetherlandsPublisher DOI
ISSN
0141-1136eISSN
1879-0291Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2018, ElsevierUsage metrics
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Keywords
Agricultural pollutionAsian sea bass (barramundi)AtrazineDiuronImidaclopridLipidsPesticidesRNA SeqScience & TechnologyLife Sciences & BiomedicineEnvironmental SciencesMarine & Freshwater BiologyToxicologyEnvironmental Sciences & EcologyGREAT-BARRIER-REEFPROLIFERATOR-ACTIVATED RECEPTORSENDOCRINE-DISRUPTING CHEMICALSHEPATIC GENE-EXPRESSIONLATES-CALCARIFERSYSTEMS TOXICOLOGYFATHEAD MINNOWSMETABOLISMBARRAMUNDIINDUCTIONEcology
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