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Transcriptomic, lipid, and histological profiles suggest changes in health in fish from a pesticide hot spot

journal contribution
posted on 2018-09-01, 00:00 authored by Sharon E Hook, Julie MondonJulie Mondon, Andrew T Revill, Paul A Greenfield, Rachael A Smith, Ryan D R Turner, Patricia CorbettPatricia Corbett, Michael St J Warne
Barramundi (Lates calcarifer) were collected at the beginning (1st sampling) and end (2nd sampling) of the wet season from Sandy Creek, an agriculturally impacted catchment in the Mackay Whitsundays region of the Great Barrier Reef catchment area, and from Repulse Creek, located approximately 100 km north in Conway National Park, to assess the impacts of pesticide exposure. Gill and liver histology, lipid class composition in muscle, and the hepatic transcriptome were examined. The first sample of Repulse Creek fish showed little tissue damage and low transcript levels of xenobiotic metabolism enzymes. Sandy Creek fish showed altered transcriptomic patterns, including those that regulate lipid metabolism, xenobiotic metabolism, and immune response; gross histological alterations including lipidosis; and differences in some lipid classes. The second sampling of Repulse Creek fish showed similar alterations in hepatic transcriptome and tissue structure as fish from Sandy Creek. These changes may indicate a decrease in health of pesticide exposed fish.

History

Journal

Marine environmental research

Volume

140

Pagination

299 - 321

Publisher

Elsevier

Location

Amsterdam, The Netherlands

ISSN

0141-1136

eISSN

1879-0291

Language

eng

Publication classification

C Journal article; C1 Refereed article in a scholarly journal

Copyright notice

2018, Elsevier