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Tuneable nanochannel formation for sample-in/answer-out devices
journal contribution
posted on 2013-04-01, 00:00 authored by A I Shallan, A J Gaudry, Rosanne GuijtRosanne Guijt, M C BreadmoreControl of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.
History
Journal
Chemical communicationsVolume
49Issue
27Pagination
2816 - 2818Publisher
Royal Society of ChemistryLocation
Cambridge, United KingdomPublisher DOI
eISSN
1364-548XLanguage
engPublication classification
C Journal article; C1.1 Refereed article in a scholarly journalCopyright notice
2013, The Royal Society of ChemistryUsage metrics
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No categories selectedKeywords
AnimalsCattleDimethylpolysiloxanesMicrofluidic Analytical TechniquesNanoparticlesNanoporesNanostructuresParticle SizeRhodaminesSerum Albumin, BovineSurface PropertiesScience & TechnologyPhysical SciencesChemistry, MultidisciplinaryChemistryMICROCHIP CAPILLARY-ELECTROPHORESISMICROFLUIDIC DEVICECONCENTRATION POLARIZATIONSEPARATIONPRECONCENTRATIONTRANSPORTJUNCTIONLITHIUMQUININEPROTEINS
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