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Waist circumference has heterogeneous impact on development of diabetes in different populations : Longitudinal comparative study between Australia and Iran

journal contribution
posted on 2010-04-01, 00:00 authored by N Rostambeigi, J Shaw, R Atkins, A Ghanbarian, Adrian CameronAdrian Cameron, A Forbes, A Momenan, F Hadaegh, P Mirmiran, P Zimmet, F Azizi, A Tonkin
Aims : Comparing waist circumference (WC) role in diabetes risk prediction and diagnosis of metabolic syndrome (MS) in different populations.

Methods : Population-based samples from Australia (n = 9026) and Iran (n = 8259) were studied in 2000 and followed for 4 years. Follow-up attendance was 58% and mean age was 51 vs. 47. Pearson correlations calculated between WC and other MS components. ROC for the role of WC in the prediction of incident diabetes was used.

Results : Prevalences of MS (48% vs. 28%), an increased WC (58.5% vs. 54.5%), low HDL-C (35% vs. 11.2%), high triglyceride (52.2% vs. 29.6%) were significantly higher in Iran. Fasting glucose ≥5.6 mmol/L was higher in Australia (26% vs. 23%). Hypertension was no different (38%). Pearson correlations between WC and other MS components were stronger in Australians: FPG (0.32 vs. 0.2), HDL (0.47 vs. 0.16), TG (0.38 vs. 0.30) and SBP (0.38 vs. 0.36). Among women, area under ROC curve for WC as a predictor for diabetes was significantly higher for Australians (0.76 vs. 0.68, p < 0.001) with no difference among men (0.69 vs. 0.71, p = 0.4).

Conclusion : WC was more strongly related to other components of MS in Australia. Association between WC and MS or incident diabetes varies between ethnicities.

History

Journal

Diabetes research and clinical practice

Volume

88

Issue

1

Pagination

117 - 124

Publisher

Elsevier Science Publishers B.V.

Location

Amsterdam, The Netherlands

ISSN

0168-8227

eISSN

1872-8227

Language

eng

Publication classification

C1.1 Refereed article in a scholarly journal

Copyright notice

2009, Elsevier Ireland Ltd.