ward-zebrafishasamodel-2015.pdf (9.09 MB)
Zebrafish as a model for leukemia and other hematopoietic disorders
journal contribution
posted on 2015-01-01, 00:00 authored by Parisa Rasighaemi, Faiza Basheer, Clifford LiongueClifford Liongue, Alister WardAlister WardZebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
History
Journal
Journal of hematology & oncologyVolume
8Issue
29Pagination
1 - 10Publisher
BioMed CentralLocation
London, Eng.Publisher DOI
eISSN
1756-8722Language
engPublication classification
C Journal article; C1 Refereed article in a scholarly journalCopyright notice
2015, BioMed CentralUsage metrics
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No categories selectedKeywords
LeukemiaMyelodysplastic syndromeMyeloproliferative disorderZebrafishScience & TechnologyLife Sciences & BiomedicineOncologyHematologyACUTE LYMPHOBLASTIC-LEUKEMIAACUTE MYELOID-LEUKEMIAT-CELL LEUKEMIATRANSGENIC ZEBRAFISHSTEM-CELLSDEFINITIVE HEMATOPOIESISCONSTITUTIVE ACTIVATIONMYELOGENOUS LEUKEMIAADULT ZEBRAFISHMYC ONCOGENE
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